CANHelp Working Group Treatment Trials

• Status: Completed
• Trial end date: 2019-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The CANHelp Working Group Treatment Trials are part of a comprehensive research program carried out by the Canadian North Helicobacter pylori (CANHelp) Working Group. The treatment component involves a series of community-specific trials designed with community input and varying on the specific treatment regimens and number of treatment arms among other study details.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Alberta
• Collaborators: Alberta Innovates Health Solutions; ArcticNet; Canadian Institutes of Health Research (CIHR)
• Treatments: Amoxicillin; Bismuth; Bismuth subsalicylate; Clarithromycin; Metronidazole; Rabeprazole; Tetracycline

Criteria

Inclusion Criteria:

• Over 15 years of age

• Identified as H. pylori infected with a positive urea breath test and/or biopsy-based evidence of H. pylori infection

Exclusion Criteria:

• Allergy to amoxicillin, metronidazole or clarithromycin

• Antibiotic therapy within 4 weeks prior to randomization

• Pregnant or breastfeeding

• Severe cardio-respiratory, pulmonary, endocrine, hepatic or renal disease