CBD-Microglia PET Study

• Status: Recruiting
• Trial end date: 2023-03-01
• Target enrollment: 0
• Participant gender: All

Summary

This study aims to examine the effect of cannabidiol (CBD) pre-treatment on brain microglial activation in healthy human subjects. Secondarily, this study aims to examine the effect of cannabidiol (CBD) pre-treatment on central pain-sensitization in healthy human subjects.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Yale University
• Collaborator: National Center for Complementary and Integrative Health (NCCIH)
• Treatments: Capsaicin

Criteria

Inclusion Criteria:

1. Men and women aged 18- 55 years

2. No significant medical or neurological illness

3. No implanted metal devices that may pose a risk during MRI scanning

4. Within the annual permissible radiation exposure

5. Able to provide written informed consent.

Exclusion Criteria:

1. Current use of any medications

2. Presence of metal in the body

3. Pregnancy or lactation