CBT Versus Selective Serotonin Reuptake Inhibitor For Treatment Of Depression In Temporal Lobe Epilepsy Patients

• Status: Completed
• Trial end date: 2014-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the study is to compare the effect of group-cognitive-behavioral therapy (CBT)versus treatment as usual with the selective serotonin reuptake inhibitor sertraline, in patients with diagnosis of temporal lobe epilepsy (TLE) and depressive disorder.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez
• Treatments: Antidepressive Agents; Serotonin; Serotonin Uptake Inhibitors

Criteria

Inclusion Criteria:

• With Major depressive disorder according to criteria from the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV)

• Diagnosed with TLE according to the criteria of the International League Against Epilepsy

• Literates had sign an informed consent

• Patients on antidepressant treatments will be allowed to participate only if they had been at stable doses for more than 8 weeks and still show signs of significant depression

Exclusion Criteria:

• Patients with high risk of suicide who required hospitalization

• Patients who abused or are dependent on drugs

• Those with a history of head trauma six months prior to the interview

• Patients who have any condition that would prevent them from understanding the study or the psychotherapeutic process, such as mental retardation, psychosis, delirium, dementia, etc

• Patients who have previously received CBT

• Patients who have started, an antidepressant drug the last 8 weeks