Overview

CD19 Chimeric Antigen Receptor (CAR) T Cells for Adults With Recurrent or Refractory B Cell Malignancies

Status:
Recruiting
Trial end date:
2034-12-31
Target enrollment:
Participant gender:
Summary
In this protocol, the investigators hypothesize that modifying the process of producing CAR+ T-cells can help to improve responses and reduce toxicities. Building on previous in vitro studies that have shown successful production of CAR+ T-cells using a new production approach, the investigators are now studying the ability to produce these CAR+ T-cells and determine how well they work in the clinical setting.
Phase:
Phase 1
Details
Lead Sponsor:
Loyola University
Collaborator:
Leukemia Research Foundation
Treatments:
Cyclophosphamide
Fludarabine
Fludarabine phosphate