CEV With/Without Periocular Carboplatin Chemotherapy for Extraocular Retinoblastoma

• Status: Completed
• Trial end date: 2014-04-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will evaluate a uniform chemotherapy protocol for nonmetastatic extraocular retinoblastoma

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Sun Yat-sen University
• Treatments: Carboplatin; Etoposide; Etoposide phosphate; Vincristine

Criteria

Inclusion Criteria:

• IRSS stage II or stage IIIa RB patients.

• for patients with IRSS stage II disease, if scleral surface invasion alone was observed, only systemic chemotherapy was administered, whereas other IRSS stage II and IIIa patients received systemic chemotherapy plus additional local chemotherapy.

• no tumor-related treatment was given prior to this chemotherapy regimen.

Exclusion Criteria:

• metastasis, including lymph node metastasis.

• the diagnosis of IRSS stage I or above in the non-target eye.