CHIZAP: Community- and Health Facility-Based Intervention With Zinc as Adjuvant Therapy for Childhood Pneumonia

• Status: Completed
• Trial end date: 2008-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the study described is to measure the degree with which zinc given as adjunct therapy to standard antibiotic treatment during childhood pneumonia reduces the risk of treatment failure and the duration of the illness.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Centre For International Health
• Collaborators: All India Institute of Medical Sciences, New Delhi; IRD, Epidemiologie et Prevention, Montpelier, France; Society for Applied Studies; Statens Serum Institut; Tribhuvan University, Nepal
• Treatments: Zinc

Criteria

Inclusion Criteria:

• Pneumonia: Child presenting with cough or difficult breathing and elevated respiratory rate.

• Severe pneumonia: Child presenting with cough or difficult breathing and chest indrawing , but without any of the following danger signs:

• not able to drink/breastfeed,

• vomit everything,

• has had convulsions,

• is lethargic or unconscious.

• Must be able to take Zinc

Exclusion Criteria:

• The child requires special care for severe illness other than pneumonia

• Severe malnutrition defined as being < 70% National Center for Health Statistics (NCHS) median weight for height

• Presence of congenital heart disease

• Documented tuberculosis

• Any antibiotic treatment during the last 48 hours

• The child was enrolled less than 6 months ago

• Presence of dysentery

• Cough for more than 14 days