CIK Cell Transfusion Plus Chemotherapy as Adjuvant Therapy for Stage IB-IIIA Non-Small Cell Lung Cancer (NSCLC)
Status:
Withdrawn
Trial end date:
2020-12-01
Target enrollment:
Participant gender:
Summary
Non - small cell lung cancer ( NSCLC ) accounts for more than 80% of lung cancer. The main
treatment for early stage patients is surgical resection, but about 30% -70% patients will
relapse. Postoperative chemotherapy is the major systemic treatment for surgical resection
NSCLC patients. However, data show only 5-10% improvement in overall survival with systemic
adjuvant chemotherapy. It is necessary to further improve the survival time of patients with
lung cancer. Biological treatment is becoming a new treatment modality for Cancer following
with surgery, radiotherapy and chemotherapy, and has been confirmed as an effective adjuvant
treatment in comprehensive cancer treatment. Cytokine induced killer cells ( CIK)
characterized as fast amplification, strong anti-cancer activity and broad anti-tumor
spectrum is most widely used and thought to be the first choice for the new generation of
anti-tumor adoptive immunotherapy. This Phase II study is investigating the efficacy of
Autologous Cytokine-Induced Killer Cell Transfusion plus Chemotherapy as adjuvant therapy for
stage IB-IIIA NSCLC.