Overview

COVidIVERmectin: Ivermectin for Treatment of Covid-19

Status:
Terminated
Trial end date:
2021-06-08
Target enrollment:
Participant gender:
Summary
Prospective, multi-centre, randomized, double-blind trial to assess efficacy and safety of ivermectin for the treatment of initial infection with SARS-CoV2 infection. Study arms: A) placebo B) ivermectin 600 μg/kg daily for 5 consecutive days (I_600) + placebo. C) ivermectin 1200 μg/kg daily at empty stomach with water for 5 consecutive days (I_1200). Patients will be randomized at emergency room of hospitals as well as at outpatient ambulatory care as well as at home, according to routine procedures of recruiting centres. In arm A and B, the number of placebo tablets to be administered will be calculated by the study dedicated pharmacist considering the number of tablets that should be taken in case a patient with the same weight is assigned to arm C.
Phase:
Phase 2
Details
Lead Sponsor:
IRCCS Sacro Cuore Don Calabria di Negrar
Collaborator:
Istituto Di Ricerche Farmacologiche Mario Negri
Treatments:
Ivermectin