COX-2 Inhibitor Versus Glucocorticoid Versus Both Combined
Status:
Completed
Trial end date:
2009-12-01
Target enrollment:
Participant gender:
Summary
Recent studies on molar surgery have shown that a combination of a glucocorticoid and NSAID
or COX-2 selective inhibitor gives better pain relief than either of the drugs used
separately. The investigators group has also shown that adding dexamethasone on top of a
regimen of paracetamol, NSAID and local anesthesia resulted in 45% painfree patients at rest
after ambulatory breast cancer surgery.
The goal of this study is to test the NSAID + glucocorticoid concept in ACl repair. The
investigators want to evaluate whether a selective COX-2 selective inhibitor or a
glucocorticoid or a combination of both drugs, as part of a multimodal analgesic regime, can
provide improved pain relief and shorter hospital stay in patients undergoing outpatient ACL
surgery.