COmbined N-acetylcysteine and Bicarbonate in PCI To Reduce Adverse Side Effect of contrasT
Status:
Completed
Trial end date:
2013-06-01
Target enrollment:
Participant gender:
Summary
This is a randomised controlled trial to investigate the efficacy of preventive regimen of
hydration with high dose oral N-acetylcysteine and intravenous sodium bicarbonate
pretreatment in patients with stable advanced renal insufficiency (CKD stage 3 and 4:GFR
15-60ml/min/1.73m2 calculated by Modification of Diet in Renal Disease Study equation (MDRD
formula)) undergoing elective percutaneous coronary intervention (PCI).