The aim of this study is to compare the effect of combined immunosuppressive therapy given on
the top standard medical therapy of chronic heart failure according to current guidelines
with standard medical therapy of chronic heart failure alone in patients with infammatory
cardiomyopathy (ICM).
Suitable subjects are characterized by EMB established presence of myocardial inflammation /
negative polymerase chain reaction assay (PCR) findings of cardiotropic infectious agents and
with varying duration of heart failure symptoms and left ventricular (LV) systolic
dysfunction (phase A).
Further, to compare the effect of two regimens of combined immunosuppressive therapy in these
patients with ICM (phase B).
Phase:
Phase 3
Details
Lead Sponsor:
St. Anne's University Hospital Brno, Czech Republic