Calcineurin Inhibitor (CNI) Versus Steroid Cessation in Renal Transplantation
Status:
Unknown status
Trial end date:
2015-04-01
Target enrollment:
Participant gender:
Summary
This study intends to determine whether steroid withdrawal or calcineurin inhibitor
withdrawal is superior for graft function and graft survival. Secondary endpoints for this
study are: incidence of tumors and cardiovascular events.
The primary objective: To assess if superior graft function (glomerular filtration rate (GFR)
difference of 10 ml/min) will be achieved at 1 year after transplantation in cohorts of de
novo kidney transplant patients treated with Myfortic-everolimus plus steroids compared to
Myfortic-cyclosporine.
Phase:
Phase 4
Details
Lead Sponsor:
University Hospital, Antwerp
Collaborators:
Erasme University Hospital Novartis Pharmaceuticals Universitair Ziekenhuis Brussel University Hospital of Liege University Hospital, Ghent University of Liege