Calcitriol and Docetaxel in Treating Patients With Metastatic or Locally Advanced Pancreatic Cancer
Status:
Completed
Trial end date:
2006-08-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Calcitriol may cause pancreatic cancer cells to look more like normal cells, and
to grow and spread more slowly. Drugs used in chemotherapy, such as docetaxel, work in
different ways to stop the growth of tumor cells, either by killing the cells or by stopping
them from dividing. Calcitriol may also help docetaxel work better by making the tumor cells
more sensitive to the drug. Giving calcitriol together with docetaxel may kill more tumor
cells.
PURPOSE: This phase II trial is studying how well giving calcitriol together with docetaxel
works in treating patients with metastatic or locally advanced pancreatic cancer.