Calcium Chloride for Prevention of Uterine Atony During Cesarean
Status:
Recruiting
Trial end date:
2023-03-30
Target enrollment:
Participant gender:
Summary
In this pilot study, investigators will administer calcium chloride or placebo to pregnant
women undergoing Cesarean delivery who have been identified as high risk for hemorrhage due
to poor uterine muscle contraction, or atony. They will assess whether a single dose of
calcium given immediately after the delivery of the fetus decreases the incidence of uterine
atony and bleeding for the mother. The pharmacokinetics of calcium chloride in pregnant women
will also be established. Data from this pilot study of 40 patients will be used to determine
sample size and appropriateness of a larger randomized clinical trial.