Calcium Supplementation to Prevent Preeclampsia in Sichuan Province of China

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: Female

Summary

the purpose of this study is to determine whether calcium supplementation is effective to prevent preeclampsia in Sichuang Province of china and which dose is more suitable

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: West China Second University Hospital
• Collaborators: Chengdu Women's and Children's Central Hospital; pengzhou shi fuyou baojianyuan; people's hospital of Guang'an; Sichuan Academy of Medical Sciences; Sichuan Provincial Maternal and Child Health Care Hospital; Suining Central Hospital; The first people's hospital of Neijiang
• Treatments: Calcium; Calcium, Dietary

Criteria

Inclusion Criteria:

• Nulliparity;age ≥35 years;Previous pre-eclampsia;Family history of pre-eclampsia;Multiple pregnancy;Time between pregnancies ≥10years;Body mass index ≥25;diastolic pressure ≥ 80 mm Hg before 20 weeks' gestation;Proteinuria ≥+ on more than one occasion or ≥ 300 mg/24 h before 20 weeks' gestation;Underlying medical conditions(Pre-existing hypertension;Pre-existing renal disease;Pre-existing diabetes;Presence of antiphospholipid antibodies;Chronic autoimmune disease);male sex partner's predecessor wife has Previous pre-eclampsia

Exclusion Criteria:

• first prenatal visit after 16 weeks' gestation;severe anemia;other Underlying medical conditions which need treatment first (such as uncontrolled hyperthyreosis )