Calcium and Vitamin D vs Markers of Adenomatous Polyps

• Status: Completed
• Trial end date: 2013-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to test whether calcium and/or vitamin D supplementation favorably affects a set of biomarkers of risk for colon cancer in persons who are at higher than average risk for colon cancer (ie, have already undergone the removal of adenomatous polyps, which are known to be precursors to developing colon cancer).

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Emory University
• Collaborators: National Cancer Institute (NCI); National Institutes of Health (NIH)
• Treatments: Calcium; Calcium Carbonate; Calcium, Dietary; Cholecalciferol; Ergocalciferols; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

• age 30-74

• adenomatous colon polyp within past 3 years

• general good health with life expectancy of at least 2 years

• available for 8 months and able to come for clinic visits

Exclusion Criteria:

• cancer within 5 years

• active major disease

• renal impairment

• history of kidney stones

• significant dietary change or weight loss within past 6 months

• unable to forego usual calcium or vitamin D use during study