Calcium for Prevention of Ovarian Hyperstimulation Syndrome

• Status: Completed
• Trial end date: 2013-09-01
• Target enrollment: 0
• Participant gender: Female

Summary

There are many protocols for prevention of ovarian hyperstimulation syndrome, intravenous calcium is a novel protocol. But still there is lack of evidence of it is real effect in prevention of OHSS & the mechanism of its action is still questionable . In the study the investigators try to search for the evidence for its effect & the real mechanism for its action.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Cairo University
• Treatments: Calcium; Calcium, Dietary

Criteria

Inclusion Criteria:

• infertile women aged 20 to 38 years.

• BMI ranged from 18 to 40.

• serum FSH within normal limits( 1-12IU /l)

• presented with ovarian response suggestive of being at risk of developing OHSS because of the presence of at least 15 follicles of 10 mm or greater on the day of hCG administration.

Exclusion Criteria:

• endocrinopathies.

• a systemic disease.

• using any medication (e.g., insulin-sensitizing drugs and GnRH antagonists.

• patients need coasting for high risk of OHSS.

• patients need cycle cancellation.

• severe male infertility requiring testicular sperm extraction.