Can Parecoxib Reduce Post-operative Ipsilateral Shoulder Pain?

• Status: Completed
• Trial end date: 2016-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare the efficacy of parecoxib with placebo on the incidence and severity of postthoracotomy shoulder pain, the amount of analgesic requirement for relieving severity of postthoracotomy shoulder pain and adverse events associated with treatment.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Chiang Mai University
• Treatments: Parecoxib

Criteria

Inclusion Criteria:

• American Society of Anesthesiology (ASA) physical status I-III

• Undergoing pulmonary resection by open thoracotomy

Exclusion Criteria:

• Unable to understand numeric rating scale despite preoperative coaching

• Preexisting shoulder pain at the same operative side

• Having contraindication for thoracic epidural analgesia

• History of previous myocardial ischemia or cerebrovascular accident

• Allergic to NSAIDS, sulfonamides or parecoxib

• Hepatic or renal impairment

• History of current gastrointestinal symptoms

• Fluid retention or congestive heart failure

• Pregnancy