Cangrelor in ST-Elevation Myocardial Infarction to Decrease Infarct Size

• Status: Terminated
• Trial end date: 2019-05-01
• Target enrollment: 0
• Participant gender: All

Summary

This study evaluates differences in the extent of myocardial necrosis noted by cardiac MRI in patients with ST-elevation myocardial infarction randomized to receive cangrelor during their percutaneous coronary intervention and compares them to patients randomized to not receive cangrelor.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: George Bennet, MD; Khaled Ziada, MD
• Treatments: Cangrelor

Criteria

Inclusion Criteria:

• Patients with an acute STEMI with the University of Kentucky as the institution of presentation with plans for PCI

• English-speaking

Exclusion Criteria:

• Pregnant patients

• Prisoners

• Patients who are unable to provide his/her own consent

• Patients with a prior history of myocardial infarction

• Patients who have received thrombolytics

• Patients on systemic anticoagulation

• Patients who are hemodynamically unstable with evidence of shock

• Patients who are mechanically intubated

• Patients with devices not MRI compatible

• Patients with chronic kidney disease, glomerular filtration rate less than 30

• Patients who are already on dual antiplatelet therapy