Capecitabine, Oxaliplatin, and Gefitinib in Treating Patients With Metastatic Colorectal Cancer
Status:
Terminated
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as capecitabine and oxaliplatin, work in
different ways to stop tumor cells from dividing so they stop growing or die. Gefitinib may
stop the growth of tumor cells by blocking the enzymes necessary for their growth. Combining
capecitabine and oxaliplatin with gefitinib may kill more tumor cells.
PURPOSE: This phase I/II trial is studying the side effects and best dose of capecitabine
when given together with oxaliplatin and gefitinib and to see how well they work in treating
patients with metastatic colorectal cancer.