Capecitabine, Oxaliplatin, and Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer
Status:
Completed
Trial end date:
2012-07-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as capecitabine and oxaliplatin, work in
different ways to stop tumor cells from dividing so they stop growing or die. Capecitabine
may stop the growth of tumor cells by stopping blood flow to the tumor. Radiation therapy
uses high-energy x-rays to damage tumor cells. Capecitabine and oxaliplatin may make tumor
cells more sensitive to radiation therapy. Combining capecitabine and oxaliplatin with
radiation therapy may kill more tumor cells.
PURPOSE: This phase II trial is studying how well giving capecitabine and oxaliplatin
together with radiation therapy works in treating patients with stage II or stage III anal
cancer.