Capsaicin Patches In Knee Osteoarthritis In Obese Patients

• Status: Terminated
• Trial end date: 2018-12-01
• Target enrollment: 0
• Participant gender: All

Summary

To assess the efficacy and safety of high concentration capsaicin patches in pain due to osteoarthritis (OA) of the knee in patients with obesity

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Nadine ATTAL
• Treatments: Capsaicin

Criteria

Inclusion Criteria:

• Enrolled patients will be males or females,

• aged over 18 years,

• have pain for at least 3 months due to mild to moderate osteoarthritis of the knee (meeting American College of Rheumatology clinical and radiographic criteria), of at least moderate intensity (pain intensity score over the last 24 hours before enrolment ≥ 4/10),

• with a BMI above 30 kg/m²

• and no other pain conditions accounting for their disability.

• The skin will be intact and no blessed.

• All female patients should take contraception during all study and at least 30 days after closer.

• All patients must sign informed consent.

• All patients will be recruited from the Department of Nutrition, Ambroise Paré University Hospital and treatment will be given during a dedicated day care clinic.

Exclusion Criteria:

• Patients necessitating surgery,

• with relative contraindications to capsaicin patches, particularly with unstable hypertension or cardiac condition,

• past history of capsaicin use will not be included.