Overview

Carbetocin Versus Oxytocin Infusion Plus Tranexamic Acid During Cesarean Section

Status:
Unknown status

Trial end date:
2021-05-01

Target enrollment:
0

Participant gender:
Female

Summary

Purpose to evaluates the effects of oxytocin infusion with or without intravenous tranexamic acid (TA) in comparison with Carbetocin for prevention of postpartum hemorrhage at a cesarean section with one or more risk factor for postpartum hemorrhage.

Phase:

N/A

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Aswan University Hospital

Treatments:

Carbetocin
Oxytocin
Pharmaceutical Solutions
Tranexamic Acid

Criteria

Inclusion Criteria:

- Women who undergo elective cesarean section with one or more risk factors for PPH were
the candidates for participation

- With fetal macrosomia, polyhydramnios, low insertion of the placenta, multiple
gestations, prolonged labor, chorioamnionitis, past history of PPH, diabetes and high
parity (5 previous deliveries).

Exclusion Criteria:

- suspected coagulopathy,

- history of coronary artery disease or hypertension,

- women with a history of hypersensitivity to carbetocin, TA or oxytocin

- general anesthesia, and

- PPH due to causes other than uterine atony.