Carbetocin on Myocardial Repolarization Dynamics in Obstetrics Study

• Status: Completed
• Trial end date: 2020-04-24
• Target enrollment: 0
• Participant gender: Female

Summary

Relationship between carbetocin dose on transmural dispersion of repolarization (TDR).

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of British Columbia
• Treatments: Carbetocin; Oxytocin

Criteria

Inclusion Criteria:

• Pregnant patients ≥ 36 weeks gestation, for elective Cesarean delivery under neuraxial anesthesia

• American Society of Anesthesiologists (ASA) class 2

• Patients ≥ 19 years of age

Exclusion Criteria:

• Long QT syndrome

• Cardiac disease or rhythm abnormalities

• Family history of long QT syndrome or abnormal cardiac conduction

• Currently taking medication that is known to prolong the QT interval

• Women who are high risk for uterine atony as outlined in SOGC

• Known allergic reaction or hypersensitivity to Carbetocin or any other oxytocin homologue

• Patients who are unable to give informed consent because of a language barrier as the study team only speaks English and will be unable to complete consent process and study procedure appropriately.