Carbetocin vs. Oxytocin for Prevention of Postpartum Bleeding in Patients With Severe Preeclampsia
Status:
Unknown status
Trial end date:
2016-01-01
Target enrollment:
Participant gender:
Summary
Postpartum hemorrhage is an important cause of maternal morbidity and mortality. In patients
with severe preeclampsia there is an increased risk of postpartum hemorrhage but the
hemodynamic changes associated with this pathology make the management of any kind of
bleeding particularly troublesome. There are many pharmacological options, being oxytocin the
first line of treatment. However there is no evidence about the safety and efficacy of
carbetocin, an oxytocin agonist. The investigators aimed to compare oxytocin with carbetocin
for the routine prevention of postpartum hemorrhage in patients with severe preeclampsia.