Overview

Cardiac (CMRI) Assessment of Acromegaly

Status:
Completed
Trial end date:
2019-02-28
Target enrollment:
Participant gender:
Summary
In this study, the investigators will evaluate the cardiac structure and function, focusing on the myocardial water content and interstitial fibrosis, in patients with active acromegaly in comparison with 1) healthy volunteers, 2) the same acromegalic patients that have received efficient therapy. The investigators hypothesize that the myocardial water content in acromegaly is increased as these patients present with sodium and water retention and that this myocardial water infiltration will improve with efficient treatment of the disease. They will thus assess using CMRI, this parameter by measuring the myocardial transverse relaxation time (T2), reflecting water content in the myocardium.
Phase:
N/A
Details
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Collaborator:
Pfizer