Cardiac Output Changes During Hyperbaric and Isobaric Bupivacaine in Patients Undergoing Cesarean Section

• Status: Completed
• Trial end date: 2016-11-15
• Target enrollment: 0
• Participant gender: Female

Summary

Spinal block leads to the reduction of systemic vascular resistance (SVR) which may effect the cardiac output. Ngan Kee et al. has showed that spina block with 0.5% hyperbaric bupivacaine for Cesarean section combined with intravenous infusion norepinephrine had higher cardiac output than those who received phenylephrine

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mahidol University
• Treatments: Bupivacaine

Criteria

Inclusion Criteria:

• American Society of Anesthesiology classification I - II

• Elective or urgency Cesarean section with spinal block e.g. cephalopelvic disproportion, premature rupture of membrane

• Singleton pregnancy

• Body mass index < 40 kg/m2

Exclusion Criteria:

• Pregnancy <35 weeks gestational age

• Hypertensive disease e.g. gestational hypertension, chronic hypertension, preeclampsia

• History of allergy to the study drugs