Cardiac and Renal Biomarkers in Arthroplasty Surgery

• Status: Terminated
• Trial end date: 2020-09-23
• Target enrollment: 0
• Participant gender: All

Summary

The investigators will compare the effect of spinal anesthesia to general anesthesia on the level of high sensitivity cardiac biomarkers in patients undergoing hip or knee arthroplasty. The investigators will also measure renal biomarkers in urine to evaluate kidney injury in the postoperative period.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Washington University School of Medicine
• Collaborators: Abbott; BioMérieux
• Treatments: Anesthetics; Anesthetics, General

Criteria

Inclusion Criteria:

• Adult patients, age 60 years or older

• Ability to provide informed consent

• American Society of Anesthesiologists (ASA) classification II or higher

Exclusion Criteria:

• Hip fracture procedures

• Contraindications to neuraxial anesthesia per The American Society of Regional Anesthesia (ASRA) guidelines

• Procedure anticipated duration is longer than expected planned spinal anesthesia duration