Cardiovascular Effects of Adderall in Healthy Adults.

• Status: Recruiting
• Trial end date: 2022-10-07
• Target enrollment: 0
• Participant gender: All

Summary

This study is designed to investigate the cardiovascular response (blood pressure, heart rate, electrocardiographic response and blood vessel reactivity response) to taking Adderall in healthy adults.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Mayo Clinic
• Treatments: Adderall

Criteria

Inclusion Criteria:

1. Adults 18 years of age and older

2. Healthy subjects without known cardiovascular disease, thyroid disease or documented mental health illness

3. Subjects who are on no medications

4. Subjects with no prior history of regular amphetamine use, and non-prescription stimulants

5. Nonsmokers

Exclusion Criteria

1. Subjects with known cardiovascular disease, thyroid disease

2. Subjects with history of psychotic disorders/mental health illness, including but not limited to anxiety, depression, bipolar disorder; history of substance abuse or dependence

3. Subjects currently taking medications

4. Prior history of regular amphetamine use, or non-prescription stimulants

5. Smokers

6. Pregnant subjects

7. Known lactose intolerance (due to presence of lactose in the prepared medication)

8. Family history of sudden cardiac death