Cardiovascular Effects of Very Low Nicotine Content Cigarettes

• Status: Not yet recruiting
• Trial end date: 2024-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The study is measuring Cardiovascular effects of very low nicotine content cigarettes on daily and non-daily smokers

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Wake Forest University Health Sciences

Criteria

Inclusion Criteria:

• Self-reported cigarette smoking at least once in the past 30 days

• ≥21 years old

• Willingness to smoke research cigarettes or usual brand cigarettes during lab visit.

• Ability to speak, comprehend, and read English sufficiently to complete study procedures

Exclusion Criteria:

• Self-reported diagnosis of cardiovascular diseases like coronary artery disease, stroke, peripheral artery disease, cardiac arrhythmia, pulmonary embolism & blood clots in legs and arm in the past 3 months

• Body temperature ≥ 100.4˙F

• Unstable health conditions interfering with electrocardiogram (ECG) measurements

• Self-reported diagnosis of hyperthyroidism or thyrotoxicosis

• Currently pregnant (as indicated by urine pregnancy test at the start of laboratory visit) or breastfeeding.

• Currently seeking treatment to quit smoking