Overview

Cardiovascular Manifestations of MR Activation in Primary Aldosteronism: Pilot Clinical Study

Status:
Not yet recruiting
Trial end date:
2026-09-01
Target enrollment:
Participant gender:
Summary
This research study aims to learn more about the impact the hormone aldosterone on the heart. Primary aldosteronism is a condition where the body's adrenal glands make too much of the hormone aldosterone, which can cause high blood pressure and increase the risk of heart and kidney disease. Treatment with medications that block aldosterone can reduce that risk. This study is trying to learn whether treatment with a medication that blocks aldosterone can improve heart function in people who make too much aldosterone.
Phase:
Phase 4
Details
Lead Sponsor:
Brigham and Women's Hospital
Treatments:
Eplerenone
Mineralocorticoid Receptor Antagonists
Mineralocorticoids