Cardiovascular and Autonomic Reactivity in Women With a History of Pre-eclampsia

• Status: Unknown status
• Trial end date: 2008-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

A history of preeclampsia is associated with a low plasma volume and higher sympathetic activity. Methyldopa will suppress sympathetic activity to normal values. In this study, the researchers will test that effect on the total cardiovascular balance.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Radboud University
• Treatments: Methyldopa

Criteria

Inclusion Criteria:

• Primiparous

• History of preeclampsia

• Low plasma volume

Exclusion Criteria:

• Thrombophilia

• Hypertension

• Auto-immune disorder

• Insulin dependent diabetes mellitus