Overview

Carfilzomib, Pomalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma

Status:
Recruiting
Trial end date:
2024-11-01
Target enrollment:
Participant gender:
Summary
The study will investigate the effects of adding carfilzomib to the combination of pomalidomide and dexamethasone in sequential dose escalation cohorts in patients with relapsed or refractory multiple myeloma. This portion of the study is complete. This study will also investigate the effects of adding daratumumab to the combination of carfilzomib, pomalidomide and dexamethasone.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
University of Chicago
Collaborators:
Multiple Myeloma Research Foundation
National Cancer Institute (NCI)
Treatments:
BB 1101
Daratumumab
Dexamethasone
Dexamethasone 21-phosphate
Dexamethasone acetate
Pomalidomide
Thalidomide