Catheter Ablation of Arrhythmias to Improve CRT Response

• Status: Terminated
• Trial end date: 2018-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to test if catheter ablation is better than medication therapy at treating arrhythmias originating from the upper and/or lower chambers of the heart in order to allow the heart to beat properly.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Kansas City Heart Rhythm Institute; University of Kansas Medical Center
• Collaborator: Biosense Webster, Inc.
• Treatments: Anti-Arrhythmia Agents

Criteria

Inclusion Criteria:

• Heart failure patients with CRT-D or CRT-P greater than 3 months

• Bi-ventricular pacing less than 94% of the time

• 3 months after CRT-D or CRT-P implantation an EF improvement less than 5%

• Presence of one of the following arrhythmias and eligible for catheter ablation:

• Atrial fibrillation

• Atrial flutter

• Supraventricular tachycardia

• Premature ventricular contraction burden greater than 30% in a 24-hour period

• Ventricular tachycardia

Exclusion Criteria:

• Estimated survival less than one year

• Patient unable to make scheduled follow up visits at treating center

• Participating in another investigational study