Catheter-based Peripheral Regional Anesthesia After Orthopedic Surgery to the Foot or Ankle

• Status: Completed
• Trial end date: 2019-02-25
• Target enrollment: 0
• Participant gender: All

Summary

BACKGROUND

Orthopedic surgery can be severely painful, and peripheral regional anesthesia is highly recommended as part of the perioperative pain treatment. Whether catheter-based techniques are better than single injection techniques are debatable. Furthermore, in catheter-based techniques, whether a low-dose automated, periodic infusion can produce similar analgesic effectiveness compared to a conventional, high dose, continuous infusion has never been explored.

AIM

Comparison of the analgesic effectiveness of a low-dose automated, periodic infusion, a conventional continuous infusion and patient-controlled boluses only in catheter-based nerve blocks for patients undergoing orthopedic surgery to the foot or ankle.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Nordsjaellands Hospital
• Collaborator: Innovation Fund Denmark
• Treatments: Ropivacaine

Criteria

Inclusion Criteria:

1. American Society of Anesthesiologists Classification I-III

2. Normal cognitive function in order to sign written, informed consent and to understand trial protocol

3. Agreement to the trial protocol, including the randomized manner

Exclusion Criteria:

1. Allergy to LA

2. Infection in or near insertion site of the peripheral nerve catheter

3. Anatomical abnormalities preventing successful peripheral nerve catheter insertion

4. Habitual use of opioids

5. Pregnancy or breastfeeding (disproved by a negative pregnancy test before trial inclusion)