Caustic Esophageal Burns in Children and High Doses of Methylprednisolone

• Status: Completed
• Trial end date: 2008-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Corrosive substance ingestion in childhood is a public health issue in developing countries and several management protocols were proposed to prevent esophageal strictures. The role of corticosteroids in preventing corrosive-induced strictures is controversial. The investigators' aim is to study the influence of high doses of corticosteroids to prevent esophageal strictures.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Sisli Etfal Training & Research Hospital; Sisli Hamidiye Etfal Training and Research Hospital
• Treatments: Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Prednisolone; Prednisolone acetate; Prednisolone hemisuccinate; Prednisolone phosphate

Criteria

Inclusion Criteria:

-Corrosive substance ingested children with grade IIb esophageal burn

Exclusion Criteria:

• Caustic substance ingested chldren grade I, IIa and grade III esophageal burns

• Caustic subtance ingested children with signs of perforation, mediastinitis, peritonitis, sespis

• Caustic substance ingested children with any chronic disease