Cavilon Breast Trial: Comparison of Cavilon Durable Barrier Cream to Glycerine ("Sorbolene") Cream

• Status: Completed
• Trial end date: 2008-10-01
• Target enrollment: 0
• Participant gender: All

Summary

This study has patients using two different moisturising creams during radiation therapy after mastectomy. These are Cavilon and sorbolene. It is hypothesised that skin reactions may be reduced by the Cavilon cream compared to sorbolene.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Trans Tasman Radiation Oncology Group; Trans-Tasman Radiation Oncology Group (TROG)
• Collaborator: 3M
• Treatments: Glycerol

Criteria

Inclusion Criteria:

• Ages 18 or more years

• Post total mastectomy

• Planned dose at least 45 Gy in 25 fractions

• ECOG 0-2

• Able to attend weekly during treatment for review and photo and for up to 6 weeks after radiotherapy

• Patients capable of childbearing using adequate contraception

• Written informed consent

Exclusion Criteria:

• Previous radiotherapy to the chest wall to be treated

• Macroscopic cutaneous involvement by malignancy at time of radiotherapy

• Known allergy to product contents

• Patients who are pregnant or lactating.