Cayenne Pepper Cataplasm - Safety Study

• Status: Completed
• Trial end date: 2016-12-15
• Target enrollment: 0
• Participant gender: All

Summary

The beneficial analgesic effects of Rubefacenciae (redden skin substances), is known since 1830 as a treatment for pain, cramps, and disorders of the musculoskeletal system. Herbal cataplasms containing rubefacient substances, such as Cayenne pepper, are commonly used as natural medications to treat painful or aching areas in the case of acute or chronic back pain, and rheumatisms. In Vienna and lower Austria, a Cayenne Pepper Cataplasm (CPC) application containing Cayenne pepper and Kaolin powder in mixed proportion, is commonly used to treat musculoskeletal conditions of pain especially of the low back. However, a concern about the safety of such applications was recently raised.

Therefore, the aims of the present study are to evaluate the effects of 10x 20min CP cataplasm application as a single treatment or in combination with electrical stimulation and massage on selected functional and molecular parameters on i) healthy subjects and ii) subjects suffering from low back pain.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Primorska
• Collaborators: Comenius University; Ludwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation; S2P, Ltd.; S2P, Science to Practice, Ltd.; Wilhelminenspital Vienna

Criteria

Inclusion Criteria:

• Chronic low back pain (>3 months)

• Body mass index below 35 kg/mˇ2

Exclusion Criteria:

• pregnancy

• sensibility disorders (e.g. due to neurological disease)

• injuries, open wounds or rash in intervention area

• known hypersensitivity against the applied substances

• HIV, Hepatitis C and other due blood communicable infectious diseases