Celecoxib, Ibuprofen and the Antiplatelet Effect of Aspirin
Status:
Completed
Trial end date:
2005-04-01
Target enrollment:
Participant gender:
Summary
Study design: Single center, placebo-controlled, double blind, parallel groups. To evaluate
the potential interaction between aspirin and ibuprofen or celecoxib in patients with
osteoarthritis (OA) and documented stable ischemic heart disease, a total of 24 patients
chronically treated with aspirin will be randomly assigned to one of the 3 treatment groups:
1) celecoxib 200 mg bid; 2) ibuprofen 600 mg tid; 3) placebo.