Celecoxib in Preventing Hand/Foot Syndrome Caused By Capecitabine With Metastatic Breast or Colorectal Cancer
Status:
Terminated
Trial end date:
2008-10-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Radiation therapy uses high energy x-rays to kill tumor cells. Drugs used in
chemotherapy, such as capecitabine, work in different ways to stop the growth of tumor cells,
either by killing the cells or by stopping them from dividing. Giving radiation therapy
together with capecitabine may kill more tumor cells. Celecoxib may prevent or lessen
hand-foot syndrome caused by capecitabine.
PURPOSE: This randomized phase III trial is studying how well celecoxib works in preventing
hand/foot syndrome caused by capecitabine in patients with metastatic breast or colorectal
cancer.