Celecoxib vs. Acetaminophen/Codeine/Caffeine for Post-operative Analgesia in Rhinoplasty.
Status:
Recruiting
Trial end date:
2020-12-01
Target enrollment:
Participant gender:
Summary
The primary aim of this study is to evaluate whether celecoxib (CELEBREX) is equivalent to
acetaminophen-codeine-caffeine (TYLENOL# 3) for the management of pain after primary elective
open septorhinoplasty with osteotomies.
Secondary objectives include comparison of adverse medication effects and complications
(e.g., bleeding events and bruising) that occur postoperatively.
Half of the study participants will receive celecoxib, and half will receive
acetaminophen-codeine-caffeine.
We hypothesize that both interventions will exhibit no difference in pain control or
postoperative bleeding, but that participants taking CELEBREX will experience less
medication-related side effects and less bruising postoperatively.