Cellular and Molecular Events During Treatment of Actinic Keratosis With Imiquimod 5% Cream

• Status: Completed
• Trial end date: 2003-07-01
• Target enrollment: 0
• Participant gender: Male

Summary

Treatment of actinic keratosis with imiquimod cream is expected to cause changes in the genes that are turned on, and turned off, by skin cells. Some of the drug induced changes in skin cells should also be visible using a special microscope. This study examines both types of changes.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Graceway Pharmaceuticals, LLC
• Treatments: Imiquimod

Criteria

Inclusion Criteria:

• Have actinic keratoses on balding scalp

• Discontinuation of tanning bed use

• Discontinuation of moisturizers

• Avoidance of retinol products

Exclusion Criteria:

• Uncontrolled, clinically significant medical condition

• Dermatologic disease other than actinic keratosis in treatment area