Central Venous and Abdominal Pressures and the Inferior Vena Cava

• Status: Unknown status
• Trial end date: 2014-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The elliptic shape of inferior vena cava (IVC) sections, while hindering the ultrasound measurement of IVC diameter, may provide a useful tool to estimate central venous pressure (CVP). Hypothetically, the higher is CVP and more the ratio R between minimum and maximum diameters approximates 1. The purpose of this study is to determine R values in four different sections before and after a fluid load test, in order to evaluate if R is affected by the test and at which level the variation is larger.

The secondary endpoint is to search for the parameter best predictive of the positivity of the fluid load test among IVC minimum and maximum diameters, eccentricity, section area, and blood velocity at the level that presented the largest variations after the fluid load.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Catholic University of the Sacred Heart

Criteria

Inclusion Criteria:

• the need determined by the attending physician to perform a rapid fluid load test to guide infusions

• a condition of adequate sedation and good adaptation to mechanical ventilation

• the presence of an arterial catheter and a catheter in the pulmonary artery

Exclusion Criteria:

• obesity (BMI> 30 kg/m2)

• age <18 years

• women of childbearing age

• tricuspid insufficiency

• hemodynamically significant right ventricular failure

• bleeding from the surgical drains greater than 150 mL in the hour preceding the enrollment

• history of allergy to colloids

• administration of more than 1000 mL of hydroxyethyl starch in the last 24 hours