Cerclage On LOw Risk Singletons: Cervical Cerclage for Prevention of Spontaneous Preterm Birth in Low Risk Singleton Pregnancies With Short Cervix

• Status: Recruiting
• Trial end date: 2025-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of this study is to evaluate the efficacy of cervical cerclage in prevention of spontaneous preterm birth in singleton pregnancies with a short transvaginal cervical length (<=25mm) and without prior spontaneous preterm birth

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Thomas Jefferson University
• Treatments: Progesterone

Criteria

Inclusion Criteria:

• 18 year old or older

• Singleton pregnancy

• No prior SPTB or second trimester losses between 160 and 366 weeks

• TVU CL ≤25mm between 180 and 236 weeks

Exclusion Criteria:

• Multiple pregnancy

• Prior SPTB or second trimester losses between 160 and 366 weeks

• Cerclage in situ

• Painful regular uterine contraction and/or preterm labor

• Rupture membranes

• Major fetal anomaly or aneuploidy

• Active vaginal bleeding

• Placenta previa and/or accreta

• Cervical dilation >1.0 cm and/or visible membranes by pelvic exam

• Suspicion of chorioamnionitis