Cervical Priming Before Dilation & Evacuation

• Status: Completed
• Trial end date: 2013-06-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to compare the efficacy of buccal misoprostol cervical priming to laminaria priming among women undergoing D&E at 13-20 weeks gestation in the Western Cape Province, South Africa

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ibis Reproductive Health
• Collaborators: Safe Abortion Action Fund of the International Planned Parenthood Federation; Society of Family Planning; Tygerberg Hospital; University of Cape Town
• Treatments: Misoprostol

Criteria

Inclusion Criteria:

• Woman seeking TOP between 13 and 20 weeks gestation as determined by ultrasound

• Age 18 or greater

• Willingness to participate in randomized study

• Fluency in English, Afrikaans or Xhosa

• Ability to give informed consent

• Staying within one hour travel time of Tygerberg Hospital for the night prior to the D&E

• Ability to be contacted by telephone

Exclusion Criteria:

• Active cervicitis

• Multiple gestation

• Fetal demise confirmed by ultrasound examination

• History of bleeding disorder or current anticoagulation therapy

• Allergy to misoprostol

• Currently breastfeeding and unwilling or unable to temporarily discard milk

• More than one prior cesarean delivery