Overview

Cetuximab, Cisplatin and BYL719 for HPV-Associated Oropharyngeal Squamous Cell Carcinoma

Status:
Withdrawn
Trial end date:
2024-08-01
Target enrollment:
Participant gender:
Summary
This study evaluates the combination of BYL719, cisplatin and cetuximab as induction chemotherapy prior to minimally-invasive transoral surgery (TORS or TLM) and selective lymph node dissection (SLND), followed by risk-adapted intensity-modulated radiation therapy (IMRT) in patients with transorally resectable, Stage III-IVa, HPV-associated oropharyngeal squamous cell carcinoma (OPSCC).
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Julie E. Bauman, MD, MPH
Collaborator:
Novartis
Treatments:
Cetuximab
Cisplatin