Challenge Test for Acetylsalicylic Acid Hypersensitivity

• Status: Unknown status
• Trial end date: 2013-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The investigators want to find new challenge test for Acetylsalicylic hypersensitivity / Aspirin hypersensitivity. The investigators suggest that this new test will be as efficient as the already established protocols in terms of sensitivity and specificity.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Helse Stavanger HF
• Collaborator: University Hospital, Akershus
• Treatments: Aspirin

Criteria

Inclusion Criteria:

• Persons between 18 and 60 years of age

• Suspected Acetylsalicylic Acid Hypersensitivity

Exclusion Criteria:

• History on anaphylactic shock after NSAIDS intake

• History on gastric ulcer after NSAIDS intake

• Patients previously gone through testing or desensitisation for Aspirin hypersensitivity

• Clinical unstable asthma or baseline FEV1<70%

• Severe disease of the heart, digestive tract, liver or kidney

• Severe chronic urticaria

• Present conjunctivitis

• Pregnancy