Overview

Change in Plaque Characteristics With Atorvastatin

Status:
Completed
Trial end date:
2012-02-01
Target enrollment:
0
Participant gender:
All
Summary
To examine effects of intensive lipid lowering therapy with atorvastatin on stabilization of coronary plaque by using optical coherence tomography (OCT) in patients with acute coronary syndrome.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Wakayama Medical University
Treatments:
Atorvastatin
Atorvastatin Calcium
Criteria
Inclusion Criteria:

- Patients with acute coronary syndrome (myocardial infarction or unstable angina) who
will undergo PCI.

- plasma LDL cholesterol levels : >=100mg/dL and ≤160mg/dL

- at least one atherosclerotic lesion of >25% stenosis other than culprit lesions of
current ACS

Exclusion Criteria:

- Patients who will undergo coronary bypass surgery.

- Patients with major complications during treatment of culprit coronary lesions.

- Patients with an atherosclerotic lesion with >50% stenosis at a left main trunk.