Changes in Cytokine Levels After Dextrose Injection in Stage IV Knee Osteoarthritis
Status:
Unknown status
Trial end date:
2020-01-01
Target enrollment:
Participant gender:
Summary
Twenty participants with severe arthritis will be enrolled. For the first week participants
will either be injected with dextrose or just have fluid withdrawn for testing. The remaining
participants will be given dextrose injection at the end of the week. After one week dextrose
injections will be given at one, two, three, four, five, and six months. Fluid will be
withdrawn from the knee at time zero, one week, and three months. The hypothesis is that
dextrose injection will cause a change in proteins in the knee consistent with improved
repair signals, along with improving knee pain and function. .