Changes in Hemorrhage With Prophylactic Oxytocin for Dilation and Evacuation

• Status: Not yet recruiting
• Trial end date: 2025-06-20
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to assess the effectiveness of prophylactic oxytocin on hemorrhage rates for second trimester dilation and evacuation (D&E) in the clinic setting.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Colorado, Denver
• Treatments: Oxytocin

Criteria

Inclusion Criteria:

• clinic-based D&E at 18 weeks gestational age and above

• speaks English or Spanish

Exclusion Criteria:

• refuses IV

• history of coagulopathy

• anticoagulant use in the preceding five days

• chorioamnionitis or sepsis

• suspected placenta accreta spectrum

• intrauterine fetal demise

• multiple gestation

• use of misoprostol for cervical preparation